Phenylpropanoids and polyketides
Medchemexpress LLC Myricetin | 529-44-2 | C15H10O8 | 25 MG
Myricetin is a plant-derived flavonoid with strong antioxidant, anticancer, antidiabetic, and anti-inflammatory properties. It exhibits scavenging activity against radicals and ions, prevents cancer cell death via apoptosis through PI3K/Akt and MAPK signaling, and shows antiphotoaging effects by quenching free radicals in the skin. It also inhibits ovarian cancer cell viability and human Hsp70.
- Strong antioxidant, anticancer, antidiabetic, and anti-inflammatory activities
- Scavenges various radicals and ions
- Prevents cancer cell death via apoptosis
- Exhibits antiphotoaging effects in skin
- Suppresses UVB-induced COX-2 expression
- Inhibits UVB-induced initiation of activator protein-1 and NF-κβ
- Inhibits Fyn kinase activity
- Inhibits viability of SKOV3 ovarian cancer cells
- Induces DNA DSBs and ER stress leading to apoptosis
- Inhibits human Hsp70
Medchemexpress LLC Myricetin-3-O-rutinoside | 41093-68-9 | 10 MG
Myricetin-3-O-rutinoside is a natural product isolated from Picea abies. It demonstrates antineuroinflammatory activity in human BV2 cells, inhibiting LPS-induced NO production. This product is for research use only.
- Isolated from Picea abies
- Antineuroinflammatory activity in human BV2 cells
- Purity of 96.98%
- Appearance as a solid, light yellow to yellow
- Classified as a flavonoid and flavonol
- Soluble in ethanol at 25 mg/mL (needs ultrasonic)
Cayman Chemical EpIgalocatechIn 25mg
A major green tea polyphenol with antioxidant, anti-inflammatory, and anticancer activities
Medchemexpress LLC Rutin (Rutoside) | 153-18-4 | 610.52 | 500 MG
Rutin (Rutoside) is a flavonoid found in many plants. It exhibits a wide range of biological activities including anti-inflammatory, antidiabetic, antioxidant, neuroprotective, nephroprotective, hepatoprotective, and reducing Aβ oligomer activities. It is also a CBR1 inhibitor and can cross the blood-brain barrier. Rutin attenuates vancomycin-induced renal tubular cell apoptosis by suppressing apoptosis, mitochondrial dysfunction, and oxidative stress.
- Anti-inflammatory activity
- Antidiabetic activity
- Antioxidant activity
- Neuroprotective properties
- Nephroprotective properties
- Hepatoprotective properties
- Reduces Aβ oligomer activities
- CBR1 inhibitor
- Can cross the blood-brain barrier
- Attenuates vancomycin-induced renal tubular cell apoptosis
Medchemexpress LLC Catechin (Standard) | 154-23-4 | 290.27 | 25 MG
Catechin (Standard) is the analytical standard of Catechin, intended for research and analytical applications. It inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM. The compound is an analytical standard grade used as a reference standard for assays and is commonly employed in qualitative, quantitative, and methodological research experiments such as HPLC, GC, and MS.
- Analytical standard for Catechin
- Intended for research and analytical applications
- Inhibits cyclooxygenase-1 (COX-1) with an IC50 of 1.4 μM
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS
- Reference standard supplied assay
Medchemexpress LLC Catechin | 154-23-4 | MFCD00075649 | 290.27 | 50 MG
Catechin, also known as (+)-Catechin, acts as an inhibitor for cyclooxygenase-1 (COX-1). It exhibits an IC50 value of 1.4 μM, highlighting its activity against this enzyme.
- Inhibits cyclooxygenase-1 (COX-1)
- Features an IC50 of 1.4 μM
Indofine Chemical Catechin With Hplc, 10 Mg
Molecular Formula: C15H14O6, Purity: 99% by HPLC, Molecular Weight: 290.27, Appearance: Light brown to Cream powder, Storage conditions: Store at 0-8C, Also known as (+)-Catechin; Cianidanol; Dexcyanidanol; Cianidol; Catergen; Drenoliver; Biocatechin; Tanningenic acid; Cyanidol; 3,3',4',5,7-Flavanepentol; 3,3',4',5,7-Pentahydroxyflavan
TARGETMOL CHEMICALS INC --GALLOCATECHIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. (-)-Gallocatechin ((−)-GC) has free radical scavenging ability and moderate affinity to the human cannabinoid receptor. purity: 99%
Abcam Epothilone D, Microtubule-stabilizing agent, 1MG
MW 491.7 Da. Microtubule-stabilizing agent. Epothilone A (ab143615) and B (ab141271) analog. Improves microtubule density and axonal integrity Shows antineoplastic and neuroprotective effects in vivo. Blood-brain barrier permeable.
The product is subject to the following: Abcam Restricted Use Statement
Medchemexpress LLC Utidelone (Epothilone D) | 189453-10-9 | C27H41NO5S | 50 MG
Utidelone (Epothilone D) is a potent microtubule stabilizer developed for research and analytical applications. It demonstrates significant cytotoxicity in human tumor cell lines, comparable to paclitaxel, and maintains its activity against multidrug-resistant cell lines. In vivo studies suggest it enhances microtubule density, axonal integrity, and cognitive functions.
- Potent microtubule stabilizer
- Exhibits cytotoxicity in human tumor cell lines
- Effective against multidrug-resistant cell lines
- Intended for research and analytical applications
- Utilized in qualitative, quantitative, and methodological experiments
- Supports HPLC, GC, and MS research
Apexbio Technology LLC Epothilone D 189453-10-9 10mg
Epothilone D (189453-10-9) is a small-molecule microtubule-stabilizing agent It is designed to stabilize microtubules thereby disrupting essential cellular processes such as mitosis Epothilone D exerts its biological activity primarily through inhibition of microtubule depolymerization In in vitro assays Epothilone D demonstrates cytotoxic activity with IC50 values of 2 9 nM in MCF-7 cells 2 7 nM in KB-31 cells and 9 5 nM in CCRF-CEM cells Based on these pharmacological properties Epothilone D holds research potential in oncology and the study of drug resistance in cancer
Apexbio Technology LLC Zearalenone(Synonyms: F-2 toxin, Mycotoxin F2, Zearalenolactone, RAL, ZEA, Zenon), 5mg, CAS: 17924-92-4.
Zearalenone (CAS 17924-92-4) is a mycotoxin produced primarily by Fusarium fungi frequently contaminating feed and food products It exhibits estrogenic activity through interaction with estrogen receptors thus altering endocrine signaling pathways Although acutely low in toxicity zearalenone effectively modulates estrogen receptor-mediated responses influencing hormonal balance in livestock species such as pigs cattle and sheep In biomedical research zearalenone serves as a tool compound to study estrogen receptor-mediated mechanisms and endocrine disruption particularly in young animals within veterinary pharmacological contexts